Original Research
Relationship between HIV stage and psychomotor speed neurocognitive score at a Kenyan sub-county hospital
Submitted: 16 October 2015 | Published: 31 August 2016
About the author(s)
Rachael N. Kinuthia, Department of Family Medicine, Moi University, Eldoret, Nairobi, KenyaJoseph M. Thigiti, Department of Family Medicine, Kenyatta University College of Health Sciences, Nairobi, Kenya
Benson N. Gakinya, Department of Mental Health, School of Medicine, Moi University, Eldoret, Nairobi, Kenya
Abstract
Objective: To determine the relationship between psychomotor speed neurocognitive score and the HIV disease stage in adults at initiation of care.
Setting: This study was conducted at Kangundo Sub-county hospital comprehensive care centre.
Methods: This was a cross-sectional study. All HIV seropositive patients aged 18 to 50 years recently initiated into care were studied. A pretested questionnaire was used to collect data. The World Health Organization (WHO) stage was used during data collection to classify study participants into asymptomatic and symptomatic groups. The grooved pegboard test was used to obtain psychomotor speed neurocognitive scores. Descriptive statistics were used to summarise data. Mann–Whitney U test, Spearman’s rho and multiple linear regression were employed in the analysis; p-value of 0.05 was considered significant.
Results: The WHO stage did not have a significant effect on the psychomotor speed neurocognitive score (p ≥ 0.05). The CD4 count had a significant effect on psychomotor speed neurocognitive score (p = 0.001).
Conclusions: There was a significant correlation between CD4 counts and psychomotor speed neurocognitive score. Efforts should be made to ensure that the CD4 counts of people living with HIV and AIDS do not continue to fall after initiation into care in order to preserve psychomotor function.
Keywords
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Crossref Citations
1. Effects of HIV infection, antiretroviral therapy, and immune status on the speed of information processing and complex motor functions in adult Cameroonians
Georgette D. Kanmogne, Julius Y. Fonsah, Anya Umlauf, Jacob Moul, Roland F. Doh, Anne M. Kengne, Bin Tang, Claude T. Tagny, Emilienne Nchindap, Léopoldine Kenmogne, Donald Franklin, Dora M. Njamnshi, Callixte T. Kuate, Dora Mbanya, Alfred K. Njamnshi, Robert K. Heaton
Scientific Reports vol: 10 issue: 1 year: 2020
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