Original Research

Capacity development of researchers involved in guideline development in Malawi, Nigeria and South Africa: A mixed-methods study

Retsedisitsoe P. Mazibuko, Willem Odendaal, Sara Cooper, Tamara Kredo, Michael McCaul, Anke Rohwer
African Journal of Primary Health Care & Family Medicine | Vol 18, No 1 | a5193 | DOI: https://doi.org/10.4102/phcfm.v18i1.5193 | © 2026 Retsedisitsoe P. Mazibuko, Willem Odendaal, Sara Cooper, Tamara Kredo, Michael McCaul, Anke Rohwer | This work is licensed under CC Attribution 4.0
Submitted: 29 August 2025 | Published: 31 March 2026

About the author(s)

Retsedisitsoe P. Mazibuko, Division of Epidemiology and Biostatistics, Department of Global Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa; and, Health Systems Research Unit, South African Medical Research Council, Cape Town, South Africa
Willem Odendaal, Health Systems Research Unit, South African Medical Research Council, Cape Town, South Africa; and, Department of Psychiatry, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa
Sara Cooper, Division of Epidemiology and Biostatistics, Department of Global Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa; and, Cochrane South Africa, South African Medical Research Council, Cape Town, South Africa; and, School of Family Medicine and Public Health, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa
Tamara Kredo, Health Systems Research Unit, South African Medical Research Council, Cape Town, South Africa; and, School of Family Medicine and Public Health, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa; and, Division of Clinical Pharmacology, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa
Michael McCaul, Division of Epidemiology and Biostatistics, Department of Global Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa
Anke Rohwer, Centre for Evidence-based Health Care, Division of Epidemiology and Biostatistics, Department of Global Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa

Abstract

Background: The Global Evidence, Local Adaptation (GELA) project aimed to build capacity for rigorous clinical practice guideline (CPG) development and evidence-informed decision-making (EDIM) in Malawi, South Africa and Nigeria.
Aim: This study aimed to explore and assess whether and how participating in GELA project activities developed the capacity of GELA researchers in evidence synthesis, guideline development, project management and interpersonal skills.
Setting: GELA researchers were based at academic and research institutions in South Africa, Malawi, Nigeria and Norway.
Methods: We conducted a nested mixed-method study of GELA researchers comprising an online survey and semi-structured interviews. Quantitative data were analysed descriptively, while qualitative data were analysed through framework analysis.
Results: Survey respondents indicated that their confidence in technical skills, as well as project management and interpersonal skills, improved during GELA. Interview results highlighted the importance of both skill sets. Collaboration emerged as a key facilitator of capacity development, while the tension between meeting deliverables and dedicating enough time to capacity development was a key challenge.
Conclusion: The GELA project enabled capacity development in technical, project management and interpersonal skills in novice as well as experienced researchers. The collaborative nature of the project facilitated this iterative process. Planning of capacity development for researchers within a project such as GELA is essential for the success of both capacity development and project deliverables.
Contribution: Our evaluation sheds light on the challenges and facilitators of building capacity of researchers within the context of a multinational project on CPG development.


Keywords

capacity development; clinical practice guidelines; evidence synthesis skills; researchers; interpersonal skills; sub-Saharan Africa

Sustainable Development Goal

Goal 3: Good health and well-being

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