Original Research
Prevalence of hypertension and associated factors in people living with HIV at Senkatana Clinic Maseru
Submitted: 30 October 2024 | Published: 22 July 2025
About the author(s)
Mosa S.M. Selebalo, Department of Family Medicine, Family Medicine Specialty Training program, Lesotho Boston Health Alliance, Maseru, Lesotho; and General Practice, Ministry of Health, Maseru, LesothoBenjamin J. Bryden, Department of Family Medicine, Faculty of Health Sciences, University of Montana, Missoula, United States of America; and Department of Family Medicine, Faculty of Health Sciences, University of Washington, Seattle, United States
David M. Thompson, Department of Biostatistics and Epidemiology, Emeritus Faculty, University of Oklahoma Health Sciences, Oklahoma City, United States
Jill E. Sanders, Department of Family Medicine, Family Medicine Specialty Training Program, Lesotho Boston Health Alliance, Maseru, Lesotho; and Department of Pediatrics, Ministry of Health, Maseru, Lesotho
Abstract
Background: Cardiovascular diseases (CVDs), including hypertension (HTN), have emerged among people living with HIV (PLHIV) as the most important prevalent contributors of non-AIDS-related mortality. Moreover, HTN itself is a modifiable risk factor for other CVDs. Data are limited regarding the prevalence of HTN and associated factors among PLHIV in Lesotho.
Aim: To determine the prevalence of HTN and associated factors among PLHIV attending Senkatana ART Clinic.
Setting: The study was carried out at Senkatana ART Clinic in urban Maseru, Lesotho.
Methods: A cross-sectional study was conducted from February to July 2022. Data were analysed using SAS statistical software (v9.4) and Microsoft Excel. To determine HTN prevalence, blood pressure (BP) was measured, and a questionnaire was administered to participants who were randomly selected using the lottery method from the clinic’s daily attendance list. Multiple logistic regression was used to assess factors associated with HTN in PLHIV while controlling for potentially confounding factors.
Results: The prevalence of HTN was 57% (exact 95% CI: 51.2%, 62.7%). Of those with HTN, 33.3% were newly diagnosed during this study (exact 95% CI: 26.3%, 40.9%), while 69% of those previously diagnosed with HTN had uncontrolled HTN at enrollment (exact 95% CI: 60.0%, 77.6%). Age older than 50 years (p < 0.0001) and a body mass index (BMI) of 25.0 kg/m2 or higher (p < 0.0002) were independently associated with HTN.
Conclusion: Hypertension was highly prevalent and poorly controlled. Factors associated with HTN in PLHIV were older age and higher BMI. The study’s findings support models of comprehensive healthcare delivery.
Keywords
Sustainable Development Goal
Metrics
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Crossref Citations
1. Intersecting epidemics: immune dysregulation associated with HIV and tuberculosis syndemic contribute to increased risk of hypertensive disease in Sub-Saharan Africa
Pheletso Letuka, Michael Z. Zulu
Frontiers in Cardiovascular Medicine vol: 12 year: 2025
doi: 10.3389/fcvm.2025.1717609

